There are 1 million people in the UK who suffer from psoriasis. 40,000 new cases of skin cancer are reported each year. 20% of all children have eczema. The number of people suffering from skin disease grows each day. The dermatological community acknowledges the significance of these figures and it is reflected by the large number of requests the British Skin Foundation receives for project funding. To stem the growth of skin disease in the UK we need to explore the causes, helping us produce effective treatments and cures.